Home Equities Score Here is the answer for the early morning surge of Sio Gene...

Here is the answer for the early morning surge of Sio Gene Therapies Inc. (SIOX) stock?

Sio Gene Therapies Inc. (NASDAQ: SIOX) stock took an aerial route in the premarket session as it rose 40.85% to $4.00 after it posted positive six-month results from a dose-escalation study of adeno-associated viral vector (AAV)9-based gene therapy candidate for GM1 gangliosidosis, from the low-dose cohort of its Phase III study. The initial results from the Phase 1/2 study of AXO-AAV-GM1 in five patients showed that the therapy was generally safe and well-tolerated, as well as an early indication for disease stabilization.

We are delighted to present promising results on the stability, tolerability, biomarker and partial efficacy of AXO-AAV-GM1, the first gene therapy tested in a GM1 gangliosidosis clinical trial, a life-limiting disorder triggered by GLB1 gene defects that inhibit the function of the beta-galactosidase enzyme. In this first-in-human trial, safety was the main measure, and we are delighted to see a favorable safety profile in the first five children treated with the low-dose,” said Gavin Corcoran, M.D., Sio Gene Therapies Chief R&D Officer.


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