Strategic Expansion Strategy Is Boosting ImmunityBio (IBRX) Shares

Following the announcement of a significant growth strategy, ImmunityBio, Inc. (NASDAQ: IBRX) has experienced a notable increase in its stock value. As of the latest session, IBRX shares have risen by 11.56%, reaching $6.95.

Initiation Of ANKTIVA Therapy In The US

ImmunityBio (IBRX) has initiated the treatment of multiple patients in the United States with ANKTIVA, its recently approved immunotherapy for Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) carcinoma in situ. The U.S. Food and Drug Administration (FDA) granted approval for ANKTIVA on April 22, 2024, for treating patients with BCG-unresponsive NMIBC CIS, both with and without papillary tumors.

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ANKTIVA, an IL-15 agonist, is administered intravesically in combination with BCG. This treatment marks the first FDA-approved immunotherapy for NMIBC that enhances the body’s NK and killer T-cell immune response to target tumor cells, while also activating memory T cells. This dual activation has led to a sustained complete response in some patients for over 47 months.

Widespread Adoption And Administration

ImmunityBio is set to provide this pioneering immunotherapy to eligible bladder cancer patients less than two months post-FDA approval. There has been substantial interest from urologists treating NMIBC, signifying a new era in immunotherapy that extends beyond checkpoint inhibitors to cytokine-based treatments.

The initial recipients of commercial doses are distributed across the U.S., with many being treated by community urologists. ANKTIVA’s administration does not require specialized handling or equipment, facilitating its use in standard medical practices.

ANKTIVA’s unique action mechanism allows urologists to administer it in their offices and clinics, thus enabling a broader patient reach within familiar settings. This advancement promises to extend the benefits of ImmunityBio’s science to an increasing number of eligible NMIBC patients.

In a related development, ImmunityBio announced in May that it had sufficient drug substance for 170,000 doses of ANKTIVA, ensuring ample supply for both commercial distribution and clinical trials.

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