Kadmon Holdings Inc. (NASDAQ: KDMN) stock gained by 1.77% at last close however the KDMN stock-price plunge by 1.09% in the pre-market trading session. Kadmon is a biopharmaceutical business that develops, manufactures, and distributes novel treatments for unfulfilled medical needs.
KDMN stock, Current Update
REZUROCKTM (belumosudil) tablets have been included to the NCCN Clinical Practice Guidelines in Oncology for Hematopoietic Cell Transplantation in the Pre-Transplant Recipient Evaluation and Management of Graft-Versus-Host Disease, according to Kadmon Holdings (GVHD). REZUROCK is currently included as a recommended systemic treatment for steroid-refractory chronic GVHD in the NCCN Recommendations in the United States, with a Category 2A classification.
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REZUROCK (belumosudil) 200 mg once daily (QD) was authorized by the US Food and Drug Administration on July 16, 2021, for the purpose of treating adult and pediatric patients 12 years and older with recurrent graft-versus-host disease (cGVHD) following failure of minimum two prior lines of systemic therapy.
REZUROCK was approved by the FDA due to the findings of ROCKstar (KD025-213) which is a randomized, open-label, multicenter pivotal study of REZUROCK in individuals with cGVHD who had two to five lines of systemic treatment. The NCCN recommendations state that “belumosudil is a potential treatment for steroid-refractory cGVHD that is well tolerated and yields clinically significant responses,” based on the ROCKstar trial.
The National Cancer Institute’s Cancer Centers Network is a non-profit organization comprised of 31 top cancer centers dedicated to patient safety, research, and education. NCCN is committed to developing and enabling cancer care that is effective, efficient, and accessible so that patients can live better lives.
Harlan W. Waksal, MD, President and CEO of KDMN Stock stated,
REZUROCK’s quick inclusion in NCCN recommendations following full FDA approval confirms the drug’s successful clinical effect in this tricky therapeutic environment. They are pleased for this significant milestone as they pursue their efforts to raise REZUROCK awareness among healthcare providers and patients with persistent GVHD.