Home Equities Score Cullinan Oncology, Inc. (CGEM) Stock Surges Following Positive Supplementary CLN-081 Study Information

Cullinan Oncology, Inc. (CGEM) Stock Surges Following Positive Supplementary CLN-081 Study Information

Cullinan Oncology, Inc. (CGEM) stock prices were up by 18.63% shortly after market trading commenced on June 4th, 2021, bringing the price per share up to USD$35.30 early on in the trading day.

CLN-081 Trial Update

The oncology company announced supplementary information about Cullinan Pearl’s ongoing Phase 1/2a trial of CLN-081 on June 4th, 2021. The trial targets patients with Non-Small Cell Lung Cancer (NSCLC) whose tumor harbor epidermal growth factor receptor (EGFR) exon 20 insertion mutations. The treatment is available orally and is an irreversible EGFR inhibitor which utilizes an innovative pyrrolopydrimidine scaffold. This scaffold is designed to selectively target cells expressing mutant EGFR variants, including exon 20 while circumventing doing damage to cells expressing wild type (WT) EGFR.


3 Tiny Stocks Primed to Explode The world's greatest investor — Warren Buffett — has a simple formula for making big money in the markets. He buys up valuable assets when they are very cheap. For stock market investors that means buying up cheap small cap stocks like these with huge upside potential.

We've set up an alert service to help smart investors take full advantage of the small cap stocks primed for big returns.

Click here for full details and to join for free

Sponsored


Details of Trial

The existing analysis of the current trial saw the evaluation of a total of 45 NSCLC patients with EGFR exon 20 insertion mutations, with each patient having been administered at least one dose of CLN-081 as of April 1st of 2021 and had been deemed evaluable for safety. The treatment was dosed orally at dosage levels that included 30, 45 65, 100, and 150 mg twice daily. As of April 1st, 2021, 42 out of the total 45 patients were response evaluable across all of the cohorts that had been tested.

Rash TREAs

Rashes were limited to Grade 1 and 2 events, with 76% of all patients have experienced an event across the range of doses administered, as of April 1st, 2021. Incidents were manageable with conventional supportive care, with no patients reporting having experienced Grade 3 or higher treatment-related rashes as an adverse event.

Diarrhea TREAs

Similarly, diarrhea was by and large limited to Grade 1 and 2 events, with incident reports of 22% across the range of doses administered as of April 1st, 2021. A single Grade 3 or higher TRAE was reported, with the patient having been administered the highest dose tested to date, 150 mg BID. The incident was resolved with supportive care, with no need for a prophylactic regimen to ameliorate the situation or severity of diarrhea.

Future Outlook for CGEM

With the recent disclosure of the additional information regarding the efficacy and safety of the CLN-081 trial, CGEM is poised to continue pushing for the speedy commercialization of their treatment. Current and potential investors are hopeful that management will continue to leverage the resources at their disposal to facilitate significant and sustained increases in shareholder value.

Get The Best Stocks To Trade Every Day!

Join now to get the NewsHeater.com pre-market morning brief 100% free

Must Read

Onesmart International Education Group Ltd. (ONE) stock surges during current market. What’s driving it high?

Onesmart International Education Group Ltd. (NASDAQ: ONE) stock gains by 111.86% in the current market trading session. OneSmart International Education is a major Chinese...

LivePerson Inc. (LPSN) stock plunge during pre-market. What’s driving it low?

LivePerson Inc. (NASDAQ: LPSN) stock gained by 0.86% at last close whereas the LPSN stock declines by 9.39% in the pre-market trading session. Through...

The Clorox Company Ltd. (CLX) stock decline during pre-market. Here’s the recent update

The Clorox Company Ltd. (NASDAQ: CLX) stock gained by 0.17% at last close whereas the CLX stock price fell by 11.59% in the pre-market....

IT Tech Packaging Inc. (ITP) stock gains during pre-market. Here’s what’s happening?

IT Tech Packaging Inc. (NASDAQ: ITP) stock gained by 7.53% at last close while the ITP stock price rises by 2.04% in the pre-market...

Why did The9 Limited (NCTY) stock turnaround in the after-hours on Friday?

The9 Limited (NCTY) shares gained 6.87% in after-hours on Friday, July 30, 2021, and closed the weekly trading at $11.98 per share. in the...

OneConnect Financial Technology Inc. (OCFT) stock plunge during current market. Here’s what you should know.

OneConnect Financial Technology Inc. (NASDAQ: OCFT) stock declines by 22.12% in the current market trading. In China, OneConnect is the most popular technology-as-a-service platform...

Invitae Corporation Inc. (NVTA) stock surge during current market. Here’s the update:

Invitae Corporation Inc. (NASDAQ: NVTA) stock gains by 12.35% in the current market trading session. Invitae Corporation is a prominent medical genetics business whose...

LivePerson Inc. (LPSN) stock plunge during pre-market. What’s driving it low?

LivePerson Inc. (NASDAQ: LPSN) stock gained by 0.86% at last close whereas the LPSN stock declines by 9.39% in the pre-market trading session. Through...

Related News

OneConnect Financial Technology Inc. (OCFT) stock plunge during current market. Here’s what you should know.

OneConnect Financial Technology Inc. (NASDAQ: OCFT) stock declines by 22.12% in the current market trading. In China, OneConnect is the most popular technology-as-a-service platform...

Invitae Corporation Inc. (NVTA) stock surge during current market. Here’s the update:

Invitae Corporation Inc. (NASDAQ: NVTA) stock gains by 12.35% in the current market trading session. Invitae Corporation is a prominent medical genetics business whose...

Alto Ingredients Inc. (ALTO) stock fall during pre-market trading. Here’s what you should know?

Alto Ingredients Inc. (NASDAQ: ALTO) stock gained by 5.99% at last close whereas the ALTO stock-price plunge by 9.89% in the pre-market trading session....

Cuentas Inc. (CUEN) stock rises during after-hour trading, given no current update.

Cuentas Inc. (NASDAQ: CUEN) stock declined by 4.68% at last close whereas the CUEN stock price gains by 2.6% in the after-market. Cuentas is...

Why did Applied DNA Sciences Inc. (APDN) stock face headwinds in the after-hours on Tuesday?

Applied DNA Sciences Inc. (APDN) shares lost 3.82% in after-hours on Tuesday, August 03, 2021, and closed the daily trading at $6.55 per share....

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Get The Best Stocks To Trade Every Day!

Join now to get the NewsHeater.com pre-market morning brief 100% free

SPECIAL GIFT

WE HAVE A GIFT FOR YOU

Download Free eBook For

7 GROWTH STOCKS FOR 2021

100% free. stop anytime no spam